Other IT companies in the top 10 include VMWare at number three while Amazon was number seven.
The e-retailing giant fell behind lesser-known British chipmaker ARM Holdings, which was named fifth, ranking well ahead of a number of tech giants.
Cambridge-based software design company ARM beat off competition from the likes of Apple and Google – both of which linger further down the list.
ARM – whose chips are used by the likes of Apple and Samsung – is one of five UK firms in the list of 100.
The Forbes list spells more bad news for Apple: once hailed as a king of innovation, the computer giant has plummeted to number 79 on the list, tumbling from 26th last year and 5th spot in 2011.